La maladie de Parkinson au Canada (serveur d'exploration)

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Radionuclide Imaging in Parkinson’s Disease: Diagnosis, Treatment, and Disease Progression

Identifieur interne : 003185 ( Main/Exploration ); précédent : 003184; suivant : 003186

Radionuclide Imaging in Parkinson’s Disease: Diagnosis, Treatment, and Disease Progression

Auteurs : Doris J. Doudet [Canada]

Source :

RBID : ISTEX:AC45DABDF59E87F02CF8A847BC9B4BE7A0211051

Abstract

This paper reviews the abilities of positron emission tomography (PET) and single photon emission tomography (SPECT) to detect Parkinson’s disease, monitor its progression and the effect of therapy. It also provides insights on the role these two modalities provide in terms of discriminating atypical syndromes from Parkinson’s disease. Both PET and SPECT are sensitive means of detecting alterations in metabolism and blood flow in the brain and impairments in neurotransmitter function, especially dopaminergic, in the striatum and, more recently, in extrastriatal structures. To date, PET presents the added advantage of quantification, better sensitivity and resolution and a greater variety of tracers for both the dopaminergic and nondopaminergic systems.

Url:
DOI: 10.1106/76VR-VNP7-T1EW-6HGY


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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   |type=    RBID
   |clé=     ISTEX:AC45DABDF59E87F02CF8A847BC9B4BE7A0211051
   |texte=   Radionuclide Imaging in Parkinson’s Disease: Diagnosis, Treatment, and Disease Progression
}}

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